Metabolomics

Metablomomics measures the concentrations of the large numbers metabolites that are present in biological tissues. Comparisons between the relative concentrations of metabolites can then be made between different population groups in order to determine differences. A variety of biological tissues can be used for analysis including plasma, urine and muscle.

Our service includes:

  • UHPLC-Q-TOF-MS/MS
  • UHPLC-ESI-MS/MS
  • UHPLC-UV/VIS
  • UHPLC-ECD
  • Analysis of:
    Amino acids
    Organic acids
    Purines & pyrimidines
    Sugars and sugaralcohols
    Acylcarnitines
    Creatinine, creatine, guanidine acetate
    Neurotransmitters
    Nucleotides
    (Targeted urinary metabolic profiling with UHPLC-Q-TOF-MS/MS in development)
    (Untargeted metabolic profiling with UHPLC-Q-TOF-MS/MS in development)
    A list of metabolites included available on request

Contact

When planning an experiment involving metabolomics, feel free to contact Jörgen Bierau, PhD for an initial consult.
E: gsm@mumc.nl