genetic cell manipulation, mechanotransduction, live imaging and confocal microscopy
J.L.V. Broers, PhD
Molecular Cell Biology
PO Box 616
6200 MD Maastricht
T: (+31) (0)43 3881366
Jos Broers, PhD completed a master degree in Biology at the University of Nijmegen in 1982. He received his PhD degree from the University of Nijmegen in 1988 on the thesis 'Intermediate filament protein expression in lung cancer'. In the periode 1989-1990 he worked as a post-doc at the the NCI/National Institute of Health, Bethesda, USA (Medical Oncology Branch). From 1990-2001 and from 2011 onwards he has worked as an assistant professor at Maastricht University, cluster Genetics and Cell Biology, department of Molecular Cell Biology. From 2001 till 2011 he worked as assistant professor at Eindhoven University of Technology, Biomechanics & Tissue Engineering (BMTE), section Soft Tissue Biomechanics and Engineering, studying the biomechanical aspects of lamin diseases.
His main research topic is to study the role of nuclear lamins in the development of diseases. After studying the role of lamins in cancer, now the main focus is on how lamins cause a variety of diseases, collectively called laminopathies. These diseases range from EDMD muscular dystrophy to Hutchinson-Gilford progeria. Despite our knowledge of the genetic failures causing these diseases, the mechanism of how mutations in a single gene can lead to at least 18 different disease phenotypes remains a mystery.
In the periods working both at the University of Eindhoven and in Maastricht Jos Broers has performed many roles in teaching at different (bio-)medical curricula (Medicine, Biomedical engineering, Biomedical Sciences), including coach, mentor, tutor, remedial teacher and lecturer.