Complex Genetics

Epidemiology of Complex Diseases

Complex chronic diseases, such as cancer, diabetes and cardiovascular diseases are caused by a complex interplay between genetic and non-genetic determinants. This interdisciplinary and intra-university team focusses on the environmental and lifestyle side of the coin and has state-of-the art expertise in epidemiology, statistics, systematic reviewing and big data, with an emphasis on cancer research. The team is based at the Maastricht Health Campus and at the Edgbaston Campus of Birmingham University UK. Their mission is to impact health via genetic epidemiological research.

Team leader

Anke Wesselius, PhD

Ongoing projects

  • A world consortium of 22 cohort and case-control studies on Bladder Cancer Epidemiology (BLEND)
  • A UK-based trial to see if selenium and vitamin E stops early bladder cancer from coming back (SELENIB)
  • A prospective cohort study and biobank of 1500 bladder cancer patients (BCPP)
  • The Maastricht Study (DMS)
  • A UK-based case-control study on prostate cancer (BiPAS)

PhD Programmes

E1: Nutritional Epidemiology (Maree Brinkman)
E2: Epidemiology of Chronic Diseases (Anke Wesselius)

Last 5 publications

  1. van Osch, F.H.M., et al., The association between smoking cessation before and after diagnosis and non-muscle-invasive bladder cancer recurrence: a prospective cohort study. Cancer Causes Control, 2018. 29(7): p. 675-683.
  2. van Osch, F.H.M., et al., A Stratified Meta-Analysis of the Association between Exposure to Environmental Tobacco Smoke during Childhood and Adulthood and Urothelial Bladder Cancer Risk. Int J Environ Res Public Health, 2018. 15(4).
  3. Jochems, S.H.J., et al., Fruit and vegetable intake and the risk of recurrence in patients with non-muscle invasive bladder cancer: a prospective cohort study. Cancer Causes Control, 2018. 29(6): p. 573-579.
  4. Jochems, S.H.J., et al., Impact of dietary patterns and the main food groups on mortality and recurrence in cancer survivors: a systematic review of current epidemiological literature. BMJ Open, 2018. 8(2): p. e014530.
  5. Vinceti, M., et al., Selenium for preventing cancer. Cochrane Database Syst Rev, 2018. 1: p. CD005195.